Fuchs’ Endothelial Dystrophy

Statistics and Associations

  • Most common hereditary endothelial (deep) corneal dystrophy
  • Strong female predilection
  • Typically develops in fourth to fifth decade of life with gradual progression
  • Leads to decreased, fluctuating vision usually worse in the morning
  • Vision decrease secondary to corneal swelling


  • Generally no treatment until substantial vision decrease
  • Endothelial keratoplasty is the main surgical intervention